Whatever season you're visiting, don't take the weather lightly — temple-tramping in the scorching afternoon sun can be a challenge, so come well-prepared. Dress lightly for the weather, but keep in mind that some palaces and all temples (notably the Grand Palace ) have a strict dress code. Also be sure, and this cannot be said enough, drink enough fluids ! You don't have a reason not to, as 7-Elevens and other convenience stores are abundant in Bangkok and they sell cooled beverages for as little as 10 baht. Locals get their water from "reverse osmosis" purified water machines that fill up a one litre bottle for one baht.
Jerry Jones is the Donald Trump of the NFL. He’s a media savant who knows how to keep boost the value of his team to astronomical levels while maintaining a dynasty of mediocrity that will follow me to the grave. I may as well be some dumb-fuck MAGA hat wearing asshole hooting and hollering as I watch Jerry drive my team in to the dumpster year after year. We got two lovable, sympathetic rookies who will either turn out to be complete assholes (Zeke) or be torn to shreds like Romo (Dak) despite having an offensive line that every sports writer claims is the best in the league. We don’t deserve the bounty that fell in our lap and Jerry will still manage to squander it.
The first report of nephrotoxicity appeared in 1964, when Paddock and colleagues reported three cases of acute renal insufficiency, two of whom were found to have calcium oxalate crystals in the renal tubules at autopsy.  In 1966, Crandell and colleagues reported a series in which 17/95 (18%) of patients developed an unusual type of nephropathy after operations in which methoxyflurane was used as a general anesthetic. This particular type of renal insufficiency was characterized by vasopressin -resistant high-output renal failure (production of large volumes of poorly concentrated urine) with a negative fluid balance, pronounced weight loss, elevation of serum sodium, chloride, osmolality and blood urea nitrogen. The urine of these patients was of a relatively fixed specific gravity and an osmolality very similar to that of the serum. Furthermore, the high urine output persisted a challenge test of fluid deprivation. Most cases resolved within 2–3 weeks, but evidence of renal dysfunction persisted for more than one year in 3 of these 17 cases (18%), and more than two years in one case (6%).