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I found an old interview with you regarding your book on Pregnenolone. Checking out your website, I notice you have warnings about dosage. Have you changed your mind? Do you think it has too many risks? For me, Pregnenolone feels like a miracle. I have suffered with vestibulitis for ten years .. all the years that my hormones have been plummeting. I am 47. I have always been fit. I believe my hormone issues are from having been on the pill for years to control endometriosis (I quit the pill ten years ago also, but I had started having symptoms before that). Anyway, I have tried every Rx, diet, PT, herb, acupuncture, etc. Bio-identical hormones gave some help. Recently I tried pregnenolone and my pain immediately decreased by 75% and I had a sudden urge to paint, which I have not done in 15 years! Do you feel it is risky for someone like me, who produces very little of any key hormones, to take pregnenolone 10mg/day? Or was that warning more for folks who still produce normal levels? I hope you'll write back. I am AMAZED to find an MD who knows what this is and what it does.
   A. I think one should be cautious taking 10 mg a day for prolonged periods. I good idea is to adjust the dosage periodically to find the lowest amount that works and to also take a couple of days off each week if possible.

Pregnenolone plays a key role in hormonal balance as a key precursor to cortisol, DHEA and progesterone, and helps to maintain balance in the body’s stress response system. In addition, pregnenolone has been shown to support a balanced mood and promote cognitive health by modulating the transmission of messages between neurons, influencing learning and memory processes. Since there is strong evidence that pregnenolone levels diminish with advancing age, restoring these levels may also help support overall brain function and sense of well-being. Each capsule of the Pregneolone formula includes 10 mg of pregnenolone in a scored, quick-dissolve tablet, allowing for incremental dosing as needed.

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