Non-steroidal anti-inflammatory drugs can have noticeable, beneficial effects for the arthritis patient. However, NSAIDs that are intended for human use have a high incidence of potentially serious side effects in dogs. NSAIDs like Etogesic, Rimadyl, Metacam, and Deramaxx have been designed specifically for dogs and are much safer than drugs like ibuprofen or aspirin. However, these “doggy” NSAIDs can still cause gastrointestinal upset and in rare cases liver or kidney dysfunction. NSAID use in dogs should always be supervised by a veterinarian.